Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And EpalrestatCrystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And Epalrestat

Structural highlights

4jir is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ALDR_HUMAN Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.

See Also

4jir, resolution 2.00Å

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