4j7e
The 1.63A crystal structure of humanized Xenopus MDM2 with a nutlin fragment, RO5524529The 1.63A crystal structure of humanized Xenopus MDM2 with a nutlin fragment, RO5524529
Structural highlights
FunctionMDM2_XENLA E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degration by the proteasome (By similarity). See Also |
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