4glw
DNA ligase A in complex with inhibitorDNA ligase A in complex with inhibitor
Structural highlights
FunctionDNLJ_STRZP DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.[HAMAP-Rule:MF_01588] See Also |
|