Crystal structure of prostaglandin F synthase from Trypanosoma cruzi bound to NADPCrystal structure of prostaglandin F synthase from Trypanosoma cruzi bound to NADP

Structural highlights

4gie is a 1 chain structure with sequence from Trypanosoma cruzi strain CL Brener. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.25Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PGFS_TRYCC Catalyzes the NADP-dependent formation of prostaglandin F2-alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p-nitrobenzaldehyde (By similarity).

See Also

4gie, resolution 1.25Å

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