4fl6

Crystal structure of the complex of the 3-MBT repeat domain of L3MBTL3 and UNC1215Crystal structure of the complex of the 3-MBT repeat domain of L3MBTL3 and UNC1215

Structural highlights

4fl6 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.55Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LMBL3_HUMAN Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells (By similarity).

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OCA