Proteopedia

4eza

Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2

Structural highlights

4eza is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.5Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

IQGA2_HUMAN Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.

4eza, resolution 1.50Å

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OCA
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