4dz0
Crystal structure of the Cu-adduct of human H-Ferritin variant MIC1 labeled with a dansyl fluorophoreCrystal structure of the Cu-adduct of human H-Ferritin variant MIC1 labeled with a dansyl fluorophore
Structural highlights
FunctionFRIH_HUMAN Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). See Also |
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