Crystal structure of the Cu-adduct of human H-Ferritin variant MIC1 labeled with a dansyl fluorophoreCrystal structure of the Cu-adduct of human H-Ferritin variant MIC1 labeled with a dansyl fluorophore

Structural highlights

4dz0 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.5Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FRIH_HUMAN Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).

See Also

4dz0, resolution 2.50Å

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