Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, rhombohedral crystal formCrystal structure of human GDP-L-fucose synthase with bound NADP and GDP, rhombohedral crystal form

Structural highlights

4b8z is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.75Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FCL_HUMAN Two step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

4b8z, resolution 2.75Å

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OCA