Crystal structure of wild-type onconase with resolution 1.46 ACrystal structure of wild-type onconase with resolution 1.46 A

Structural highlights

3phn is a 1 chain structure with sequence from Lithobates pipiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.46Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RNP30_LITPI Basic protein with antiproliferative/cytotoxic activity against several tumor cell lines in vitro, as well as antitumor in vivo. It exhibits a ribonuclease-like activity against high molecular weight ribosomal RNA.

3phn, resolution 1.46Å

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OCA