3p7o

Rat Insulin Degrading Enzyme (Insulysin) E111F mutant with two bound peptidesRat Insulin Degrading Enzyme (Insulysin) E111F mutant with two bound peptides

Structural highlights 3p7o is a 3 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.1423Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function IDE_RAT Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. See Also Insulin-degrading enzyme 3D structures

spinqualitylabelsall models 3p7o, resolution 2.14Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image