3ogl

Structure of COI1-ASK1 in complex with JA-isoleucine and the JAZ1 degronStructure of COI1-ASK1 in complex with JA-isoleucine and the JAZ1 degron

Structural highlights

3ogl is a 23 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 3.18Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

COI1_ARATH Required for jasmonate-regulated plant fertility and defense processes, and for coronatine and/or other elicitors perceptions/responses. Seems to not be required for meiosis. Required for the regulation of some genes induced by wounding, but not for all. Component of SCF(COI1) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (probably including the ribulose bisphosphate carboxylase small chain 1B RBCS-1B and the histone deacetylase HDA6). These SCF complexes play crucial roles in regulating response to jasmonate, and their interactions with the COP9 signalosome (CSN) appear to be important for their activity. Interacts with TIFY10A and inositol pentakisphosphate to form a high-affinity jasmonates coreceptor. Involved in the regulation of plant gene expression during plant-pathogen interactions with Pseudomonas syringae and Alternaria brassicicola.^[1] ^[2] ^[3] ^[4] ^[5] ^[6] ^[7] ^[8] ^[9]

References

↑ Xie DX, Feys BF, James S, Nieto-Rostro M, Turner JG. COI1: an Arabidopsis gene required for jasmonate-regulated defense and fertility. Science. 1998 May 15;280(5366):1091-4. PMID:9582125
↑ Feys B, Benedetti CE, Penfold CN, Turner JG. Arabidopsis Mutants Selected for Resistance to the Phytotoxin Coronatine Are Male Sterile, Insensitive to Methyl Jasmonate, and Resistant to a Bacterial Pathogen. Plant Cell. 1994 May;6(5):751-759. PMID:12244256 doi:10.1105/tpc.6.5.751
↑ Reymond P, Weber H, Damond M, Farmer EE. Differential gene expression in response to mechanical wounding and insect feeding in Arabidopsis. Plant Cell. 2000 May;12(5):707-20. PMID:10810145
↑ Ellis C, Turner JG. A conditionally fertile coi1 allele indicates cross-talk between plant hormone signalling pathways in Arabidopsis thaliana seeds and young seedlings. Planta. 2002 Aug;215(4):549-56. Epub 2002 Jul 4. PMID:12172836 doi:10.1007/s00425-002-0787-4
↑ Xu L, Liu F, Lechner E, Genschik P, Crosby WL, Ma H, Peng W, Huang D, Xie D. The SCF(COI1) ubiquitin-ligase complexes are required for jasmonate response in Arabidopsis. Plant Cell. 2002 Aug;14(8):1919-35. PMID:12172031
↑ Devoto A, Nieto-Rostro M, Xie D, Ellis C, Harmston R, Patrick E, Davis J, Sherratt L, Coleman M, Turner JG. COI1 links jasmonate signalling and fertility to the SCF ubiquitin-ligase complex in Arabidopsis. Plant J. 2002 Nov;32(4):457-66. PMID:12445118
↑ Feng S, Ma L, Wang X, Xie D, Dinesh-Kumar SP, Wei N, Deng XW. The COP9 signalosome interacts physically with SCF COI1 and modulates jasmonate responses. Plant Cell. 2003 May;15(5):1083-94. PMID:12724535
↑ van Wees SC, Chang HS, Zhu T, Glazebrook J. Characterization of the early response of Arabidopsis to Alternaria brassicicola infection using expression profiling. Plant Physiol. 2003 Jun;132(2):606-17. Epub 2003 May 15. PMID:12805591 doi:10.1104/pp.103.022186
↑ He P, Chintamanani S, Chen Z, Zhu L, Kunkel BN, Alfano JR, Tang X, Zhou JM. Activation of a COI1-dependent pathway in Arabidopsis by Pseudomonas syringae type III effectors and coronatine. Plant J. 2004 Feb;37(4):589-602. PMID:14756769

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OCA

[1] Xie DX, Feys BF, James S, Nieto-Rostro M, Turner JG. COI1: an Arabidopsis gene required for jasmonate-regulated defense and fertility. Science. 1998 May 15;280(5366):1091-4. PMID:9582125

[2] Feys B, Benedetti CE, Penfold CN, Turner JG. Arabidopsis Mutants Selected for Resistance to the Phytotoxin Coronatine Are Male Sterile, Insensitive to Methyl Jasmonate, and Resistant to a Bacterial Pathogen. Plant Cell. 1994 May;6(5):751-759. PMID:12244256 doi:10.1105/tpc.6.5.751

[3] Reymond P, Weber H, Damond M, Farmer EE. Differential gene expression in response to mechanical wounding and insect feeding in Arabidopsis. Plant Cell. 2000 May;12(5):707-20. PMID:10810145

[4] Ellis C, Turner JG. A conditionally fertile coi1 allele indicates cross-talk between plant hormone signalling pathways in Arabidopsis thaliana seeds and young seedlings. Planta. 2002 Aug;215(4):549-56. Epub 2002 Jul 4. PMID:12172836 doi:10.1007/s00425-002-0787-4

[5] Xu L, Liu F, Lechner E, Genschik P, Crosby WL, Ma H, Peng W, Huang D, Xie D. The SCF(COI1) ubiquitin-ligase complexes are required for jasmonate response in Arabidopsis. Plant Cell. 2002 Aug;14(8):1919-35. PMID:12172031

[6] Devoto A, Nieto-Rostro M, Xie D, Ellis C, Harmston R, Patrick E, Davis J, Sherratt L, Coleman M, Turner JG. COI1 links jasmonate signalling and fertility to the SCF ubiquitin-ligase complex in Arabidopsis. Plant J. 2002 Nov;32(4):457-66. PMID:12445118

[7] Feng S, Ma L, Wang X, Xie D, Dinesh-Kumar SP, Wei N, Deng XW. The COP9 signalosome interacts physically with SCF COI1 and modulates jasmonate responses. Plant Cell. 2003 May;15(5):1083-94. PMID:12724535

[8] van Wees SC, Chang HS, Zhu T, Glazebrook J. Characterization of the early response of Arabidopsis to Alternaria brassicicola infection using expression profiling. Plant Physiol. 2003 Jun;132(2):606-17. Epub 2003 May 15. PMID:12805591 doi:10.1104/pp.103.022186

[9] He P, Chintamanani S, Chen Z, Zhu L, Kunkel BN, Alfano JR, Tang X, Zhou JM. Activation of a COI1-dependent pathway in Arabidopsis by Pseudomonas syringae type III effectors and coronatine. Plant J. 2004 Feb;37(4):589-602. PMID:14756769

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