Crystal Structure of Transketolase Complexed with Thiamine Diphosphate from Bacillus anthracisCrystal Structure of Transketolase Complexed with Thiamine Diphosphate from Bacillus anthracis

Structural highlights

3m49 is a 2 chain structure with sequence from "ancestor" Bacillus anthracis ames "ancestor". This structure supersedes the now removed PDB entry 3k95. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , , , , , , ,
NonStd Res:
Gene:BAS3470, BA_3744, GBAA3744, GBAA_3744, tkt-2, tkt2 (Bacillus anthracis Ames "Ancestor")
Activity:Transketolase, with EC number 2.2.1.1
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[Q81Y15_BACAN] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.[RuleBase:RU004996]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3m49, resolution 2.00Å

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OCA