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Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Entamoeba histolyticaCrystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Entamoeba histolytica
Structural highlights
FunctionC4M4M6_ENTH1 This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.[RuleBase:RU367024] Evolutionary ConservationCheck, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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