Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Entamoeba histolyticaCrystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Entamoeba histolytica

Structural highlights

3lqw is a 1 chain structure with sequence from Entamoeba histolytica HM-1:IMSS. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.3Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

C4M4M6_ENTH1 This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.[RuleBase:RU367024]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3lqw, resolution 1.30Å

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