Crystal structure of NtcA in complex with 2,2-difluoropentanedioic acidCrystal structure of NtcA in complex with 2,2-difluoropentanedioic acid

Structural highlights

3la3 is a 2 chain structure with sequence from Nostoc sp. PCC 7120 = FACHB-418. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NTCA_NOSS1 Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control. Has affinity for the xisA upstream region. Binds to a 66 bp region containing three repeats of the consensus recognition sequence 5'-ACATT-3'.

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3la3, resolution 2.40Å

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OCA