3k7e

Crystal structure of human ligand-free mature caspase-6Crystal structure of human ligand-free mature caspase-6

Structural highlights

3k7e is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 3Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CASP6_HUMAN Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

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OCA

3k7e

Crystal structure of human ligand-free mature caspase-6Crystal structure of human ligand-free mature caspase-6

Structural highlights

Function

See Also

Contents

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