Following evolutionary paths to high affinity and selectivity protein-protein interactions using Colicin7 and Immunity proteinsFollowing evolutionary paths to high affinity and selectivity protein-protein interactions using Colicin7 and Immunity proteins

Structural highlights

3gkl is a 4 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CEA7_ECOLX This plasmid-coded bactericidal protein is an endonuclease active on both single- and double-stranded DNA but with undefined specificity. Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3gkl, resolution 2.20Å

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OCA