Crystal structure of the N-terminal domain of human NUDT6Crystal structure of the N-terminal domain of human NUDT6
Structural highlights
3fxt is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
NUDT6_HUMAN May contribute to the regulation of cell proliferation.[1][2]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
↑Asa SL, Ramyar L, Murphy PR, Li AW, Ezzat S. The endogenous fibroblast growth factor-2 antisense gene product regulates pituitary cell growth and hormone production. Mol Endocrinol. 2001 Apr;15(4):589-99. PMID:11266510 doi:http://dx.doi.org/10.1210/mend.15.4.0626
↑Zhang SC, Barclay C, Alexander LA, Geldenhuys L, Porter GA, Casson AG, Murphy PR. Alternative splicing of the FGF antisense gene: differential subcellular localization in human tissues and esophageal adenocarcinoma. J Mol Med (Berl). 2007 Nov;85(11):1215-28. Epub 2007 Jun 14. PMID:17569023 doi:http://dx.doi.org/10.1007/s00109-007-0219-9
