Structure of berberine bridge enzyme, C166A variant in complex with (S)-reticulineStructure of berberine bridge enzyme, C166A variant in complex with (S)-reticuline
Structural highlights
3fwa is a 1 chain structure with sequence from Eschscholzia californica. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
RETO_ESCCA Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine.
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
