3e8y
Xray structure of scorpion toxin BmBKTx1Xray structure of scorpion toxin BmBKTx1
Structural highlights
FunctionKA191_MESMA Selective inhibitor of high conductance calcium-activated potassium channels KCa1.1/KCNMA1. May be insect specific.[1] [PDB:3E8Y] Publication Abstract from PubMedRacemic protein crystallography, enabled by total chemical synthesis, has allowed us to determine the X-ray structure of native scorpion toxin BmBKTx1; direct methods were used for phase determination. This is the first example of a protein racemate that crystallized in space group I41/a. X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods.,Mandal K, Pentelute BL, Tereshko V, Kossiakoff AA, Kent SB J Am Chem Soc. 2009 Feb 4;131(4):1362-3. PMID:19133782[2] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences
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