Crystal structure of Lactate Dehydrogenase from Staphylococcus AureusCrystal structure of Lactate Dehydrogenase from Staphylococcus Aureus

Structural highlights

3d0o is a 2 chain structure with sequence from Staphylococcus aureus subsp. aureus COL. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.8Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LDH1_STAAC Appears to be the primary factor that allows S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells.[1]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Richardson AR, Libby SJ, Fang FC. A nitric oxide-inducible lactate dehydrogenase enables Staphylococcus aureus to resist innate immunity. Science. 2008 Mar 21;319(5870):1672-6. PMID:18356528 doi:http://dx.doi.org/319/5870/1672

3d0o, resolution 1.80Å

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