Leishmania naiffi uracil-DNA glycosylase in complex with 5-bromouracilLeishmania naiffi uracil-DNA glycosylase in complex with 5-bromouracil

Structural highlights

3cxm is a 1 chain structure with sequence from Leishmania naiffi. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.5Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

D0VWU0_9TRYP Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.[HAMAP-Rule:MF_03166][RuleBase:RU003780]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3cxm, resolution 1.50Å

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OCA