3aq4

Molecular insights into plant cell proliferation disturbance by Agrobacterium protein 6bMolecular insights into plant cell proliferation disturbance by Agrobacterium protein 6b

Structural highlights

3aq4 is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.8Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ARF1_ARATH GTP-binding protein involved in protein trafficking; required for the sequence-specific vacuolar sorting route to the lytic vacuole, for the ER-to-Golgi transport and for the Golgi-derived transport to the plasma membrane. Involved in the recruitment of COPI and GDAP1 to membranes.^[1] ^[2] ^[3] ^[4] ^[5]

References

↑ Lee MH, Min MK, Lee YJ, Jin JB, Shin DH, Kim DH, Lee KH, Hwang I. ADP-ribosylation factor 1 of Arabidopsis plays a critical role in intracellular trafficking and maintenance of endoplasmic reticulum morphology in Arabidopsis. Plant Physiol. 2002 Aug;129(4):1507-20. PMID:12177464 doi:http://dx.doi.org/10.1104/pp.003624
↑ Takeuchi M, Ueda T, Yahara N, Nakano A. Arf1 GTPase plays roles in the protein traffic between the endoplasmic reticulum and the Golgi apparatus in tobacco and Arabidopsis cultured cells. Plant J. 2002 Aug;31(4):499-515. PMID:12182707
↑ Pimpl P, Hanton SL, Taylor JP, Pinto-daSilva LL, Denecke J. The GTPase ARF1p controls the sequence-specific vacuolar sorting route to the lytic vacuole. Plant Cell. 2003 May;15(5):1242-56. PMID:12724547
↑ Xu J, Scheres B. Dissection of Arabidopsis ADP-RIBOSYLATION FACTOR 1 function in epidermal cell polarity. Plant Cell. 2005 Feb;17(2):525-36. Epub 2005 Jan 19. PMID:15659621 doi:http://dx.doi.org/10.1105/tpc.104.028449
↑ Matheson LA, Hanton SL, Rossi M, Latijnhouwers M, Stefano G, Renna L, Brandizzi F. Multiple roles of ADP-ribosylation factor 1 in plant cells include spatially regulated recruitment of coatomer and elements of the Golgi matrix. Plant Physiol. 2007 Apr;143(4):1615-27. Epub 2007 Feb 16. PMID:17307898 doi:http://dx.doi.org/10.1104/pp.106.094953

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OCA

[1] Lee MH, Min MK, Lee YJ, Jin JB, Shin DH, Kim DH, Lee KH, Hwang I. ADP-ribosylation factor 1 of Arabidopsis plays a critical role in intracellular trafficking and maintenance of endoplasmic reticulum morphology in Arabidopsis. Plant Physiol. 2002 Aug;129(4):1507-20. PMID:12177464 doi:http://dx.doi.org/10.1104/pp.003624

[2] Takeuchi M, Ueda T, Yahara N, Nakano A. Arf1 GTPase plays roles in the protein traffic between the endoplasmic reticulum and the Golgi apparatus in tobacco and Arabidopsis cultured cells. Plant J. 2002 Aug;31(4):499-515. PMID:12182707

[3] Pimpl P, Hanton SL, Taylor JP, Pinto-daSilva LL, Denecke J. The GTPase ARF1p controls the sequence-specific vacuolar sorting route to the lytic vacuole. Plant Cell. 2003 May;15(5):1242-56. PMID:12724547

[4] Xu J, Scheres B. Dissection of Arabidopsis ADP-RIBOSYLATION FACTOR 1 function in epidermal cell polarity. Plant Cell. 2005 Feb;17(2):525-36. Epub 2005 Jan 19. PMID:15659621 doi:http://dx.doi.org/10.1105/tpc.104.028449

[5] Matheson LA, Hanton SL, Rossi M, Latijnhouwers M, Stefano G, Renna L, Brandizzi F. Multiple roles of ADP-ribosylation factor 1 in plant cells include spatially regulated recruitment of coatomer and elements of the Golgi matrix. Plant Physiol. 2007 Apr;143(4):1615-27. Epub 2007 Feb 16. PMID:17307898 doi:http://dx.doi.org/10.1104/pp.106.094953

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