3D structures of ubiquitin conjugating enzyme

3D Structures of ubiquitin conjugating enzyme3D Structures of ubiquitin conjugating enzyme

Updated on 26-February-2024 - For a general description of the protein see Ubiquitin conjugating enzyme

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• Ubiquitin conjugating enzyme
  • 1jas – hUbc – human
    
  • 8wr5 – hUbc (mutant)
    
  • 2aak – AtUbc – Arabidopsis thaliana
    
  • 2qcq, 1fzy – yUbc – yeast
    
  • 1fxt – yUbc + ubiquitin
    
  • 2e2c – Ubc – Spisula solidissima
    
  • 1q34 – CeUbc – Caenorhabidis elegans
    
  • 2fo3 – Ubc – Plasmodium vivax
    
  • 2h2y – PfUbc – Plasmodium falciparum
    
  • 6mj9, 5vor – Ubc – Naegleria fowleri
    
  • 1yf9 – Ubc – Leishmania major
    
  • 7wlh – Ubc – African swine fever virus
    
• Ubiquitin conjugating enzyme 1
  • 2aak – AtUbc
    
  • 3we5 – Ubc – poplar mushroom
    
  • 1fzy – yUbc
    
  • 1tte – yUbc (mutant)
    
  • 1z3d – CeUbc
    
• Ubiquitin conjugating enzyme 2
  • 1ayz – yUbc
    
  • 4r62 – yUbc + ubiquitin carboxyl extension protein 80
    
  • 7mex, 7mey – yUbc + ubiquitin + degron + E3 – Cryo EM
    
  • 5aie – yUbc + NOT4
    
  • 1z2u – CeUbc
    
• Ubiquitin conjugating enzyme 3 or Ubc3 or Cdc34
  • 6nyd – yUbc
    
• Ubiquitin conjugating enzyme 4
  • 1qcq – yUbc
    
  • 5aie – yUbc + NOT4 RING domain
    
  • 4ii2 – fyUbc (mutant) + E1 + ATP – fission yeast
    
• Ubiquitin conjugating enzyme 6
  • 4jjq – hUbc + ubiquitin carboxyl terminal hydrolase
    
• Ubiquitin conjugating enzyme 7 or Ubc L3
  • 2awf, 2cyx – hUbc
    
  • 6xxu – hUbc - NMR
    
  • 7v8f – hUbc + E3
    
  • 7oik – hUbc + E3 – Cryo EM
    
  • 6xxu – hUbc - NMR
    
  • 1c4z – hUbc + E3 HECT domain
    
  • 7v8f – hUbc + E3 ubiquitin protein ligase RNF31
    
  • 8eb0 – hUbc + E3 ubiquitin protein ligase RNF216 + Ub
    
  • 1fbv – hUbc + E3 Cbl + ZAP-70 peptide
    
  • 4jqu – hUbc + U7BR
    
  • 3sqv – hUbc + secreted effector protein
    
  • 3sy2 – hUbc + E3 Sopa
    
  • 5udh – hUbc + ubiquitin + E3 ARIH1
    
  • 4q5e, 4q5h – hUbc (mutant) + ubiquitin + OspG
    
  • 6cp2 – hUbc (mutant) + UBB + SidC
    
  • 6djw, 6djx, 6n13 – hUbc (mutant) + ubiquitin + PARKIN
    
  • 5tte, 5udh – hUbc (mutant) + ubiquitin + ARIH1
    
  • 5hpt – hUbc + ubiquitin + NEDD4-like E3 ubiquitin-protein
    
  • 7b5l, 7b5n – hUbc + hPolyUBB-C + Cul1 + Nedd8 + RBX1 + ARITH1 – Cryo EM
    
  • 8pmq – hUbc in Ube2R-GID/CTLH complex – Cryo EM
    
  • 2ucz – yUbc
    
• Ubiquitin conjugating enzyme 8
  • 1y6l, 1wzw, 1wzv – hUbc
    
  • 2kjh – hUbc + ubiquitin
    
  • 4x57 – AtUbc + membrane-anchord ubiquitin-fold protein
    
• Ubiquitin conjugating enzyme 9 see SUMO conjugating enzyme Ubc9
• Ubiquitin conjugating enzyme 10 or Ubc C
  • 1i7k – hUbc (mutant)
    
  • 4yii – hUbc + anaphase-promoting complex subunit 2
    
• Ubiquitin conjugating enzyme 12 (NEDD8 conjugating enzyme; Ubc F)
  • 2edi – hUbc 2 UQ-CON domain - NMR
    
  • 1y8x – hUbc + E1 NEDD8
    
  • 1tt5 – hUbc + E1 Uba3, APPBP1 subunits
    
  • 1y8x – hUbc + E1 NEDD8
    
  • 2nvu – hUbc + E1 NEDD8 + NEDD8
    
  • 3fn1 – hUbc + E1 NEDD8-activating enzyme
    
  • 3tdu – hUbc + cullin-1 + Dcn1-like protein
    
  • 4p5o – hUbc + cullin-1 + Dcn1-like protein + Rbx1 + NEDD8
    
  • 4gao – hUbc + Dcn1-like protein
    
  • 3tdi – hUbc + defective in cullin neddylation protein
    
  • 3o2u – yUbc
    
• Ubiquitin conjugating enzyme 13 or Ubc N
  • 4fh1 – hUbc (mutant)
    
  • 1j74 – hMms2
    
  • 1j7d – hUbc/Mms2
    
  • 1jbb – yUbc
    
  • 1jat – yUbc/Mms2
    
• Ubiquitin conjugating enzyme 13 complexes
  • 2c2v – hUbc + CHIP + Uev1a
    
  • 3hct, 3hcu – hUbc + TNF receptor associated factor 6
    
  • 4dhi, 4dhz – hUbc + OTUB1 + ubiquitin + ubiquitin aldehyde
    
  • 4orh – hUbc/Mms2 + E3 Rnf8
    
  • 3von – hUbc/Mms2 + OTUB1
    
  • 1zgu – hMms2 + ubiquitin - NMR
    
  • 5eya – hUbc + ubiquitin + TRIM25 ring domain
    
  • 4tkp – hUbc + TRIM5 ring domain
    
  • 2gmi – hUbc/Mms2 (mutant) + ubiquitin
    
  • 4onl, 4onm, 4onn – hUbc + Mms2 (mutant)
    
  • 4nr3, 4nrg, 4nri – hUbc (mutant) + Mms2
    
  • 3von – hUbc + Otub1 + E2 variant
    
  • 6d6i – hUbc + ubiquitin + E2 variant
    
  • 4dhj – hUbc + ubiquitin + OTUB1
    
  • 5vnz, 5vo0 – hUbc + ubiquitin + TraF6
    
  • 6kl4, 7bxg, 6p5b, 6ulh, 6ump, 6ums – hUbc + ubiquitin + MavC
    
  • 6kfp, 6kg6 – hUbc + ubiquitin-RPS27a + MavC
    
  • 5ywr – hUbc + E3 ubiquitin-protein ligase ZANFR1
    
  • 4whv, 6s53 – hUbc + ubiquitin + E3 ubiquitin-protein ligase
    
  • 5ait, 5aiu – hUbc + ubiquitin + E3 ubiquitin-protein ligase RNF4
    
  • 7bbf, 7myh – hUbc + polyubiquitin-C
    
  • 6ulh, 6ump, 6ums, 7bxg – hUbc + polyubiquitin-C + MavC
    
  • 7bbd – hUbc + polyubiquitin-C + E3
    
  • 4orh – hUbc/Mms2 + E3 ubiquitin-protein ligase RN8
    
  • 4ip3, 3w31 – hUbc + Orf169b
    
  • 2oxq – Ubc + CHIP U-box - zebrafish
    
  • 6zhs, 6zht – yUbc + E1
    
  • 5ojw – yUbc + Mms2
    
  • 6jky – yUbc + ubiquitin + MvcA
    
  • 4dhi – CeUbc + OTUB1
    
• Ubiquitin conjugating enzyme 16 or Ubc W
  • 2mt6 – hUbc - NMR
    
  • 8a58 – hUbc + E3 ubiquitin-protein ligase TRIM21
    
• Ubiquitin conjugating enzyme 20
  • 7yw1l – Ubc – Trametes pubescens
    
• Ubiquitin conjugating enzyme A or Rad6
  • 6cyo – hUbc A
    
  • 6cyr – hUbc A (mutant)
    
  • 8btl – hUbc + Ubr4
    
  • 8iej – hUbc A in nucleosome complex – Cryo EM
    
• Ubiquitin conjugating enzyme B
  • 2yb6 – hUbc
    
  • 2y4w – hUbc - NMR
    
  • 2ybf – hUbc + Rad18
    
• Ubiquitin conjugating enzyme D1
  • 2c4p – hUbc D1
    
  • 2yho – hUbc D1 + E3 Mylip
    
  • 5fer – hUbc D1 + ubiquitin carboxyl extension protein 80 + TRIM25 ring
    
  • 4qpl – hUbc D1 + E3 ubiquitin-protein ligase RNF146
    
  • 3ptf, 6d4p, 5tut – hUbc D1 + ubiquitin
    
  • 4ap4 – hUbc D1 + E3 ubiquitin-protein ligase RNF4 + ubiquitin
    
  • 3oj4 – hUbc D1 + tumor necrosis factor α-induced protein 3 + ubiquitin
    
  • 7zj3 – hUbc D1 (mutant) + TRIM2 + p;olyubiquitin-C
    
• Ubiquitin conjugating enzyme D2
  • 2esk, 2clw, 3l1y, 3tgd – hUbc D2
    
  • 2eso, 2esp, 2esq – hUbc, 7bolD2 (mutant)
    
  • 1w4u – hUbc D2 - NMR
    
  • 4ddg, 4ddi, 5ulf – hUbc D2 + ubiquitin
    
  • 5ulf, 3a33 – hUbc D2 (mutant) + ubiquitin
    
  • 4ldt – hUbc D2 + Otub1 + ubiquitin
    
  • 5d1k, 5d1l, 5d1m – hUbc D2 + E3 ubiquitin-protein ligase RNF25
    
  • 8gbq – hUbc D2 + E3 ubiquitin-protein ligase RNF125
    
  • 5edv – hUbc D2 + ubiquitin + E3 ubiquitin-protein ligase RNF31
    
  • 4a49 – hUbc D2 + E3 ubiquitin-protein ligase CBL-B
    
  • 4v3k, 4v3l, 4a4b, 4a4c – hUbc D2 + ZAP peptide + E3 ubiquitin-protein ligase CBL-B
    
  • 3zni, 6w9d, 6w7z, 5ulh, 5vzw, 5zbu – hUbc D2 + ubiquitin + E3 ubiquitin-protein ligase
    
  • 6sqo, 6sqs, 6sqr – hUbc D2 + ubiquitin-RPS27a + E3 ubiquitin-protein ligase Mdm2
    
  • 5ulh, 5ulk – hUbc D2 (mutant) + ubiquitin + E3 ubiquitin-protein ligase RNF165
    
  • 5mnj – hUbc D2 (mutant) + UBB + Mdm2 + Mdm4
    
  • 5d0k, 5d0m – hUbc D2 + UBB + RING finger protein 165
    
  • 4ldt – hUbc D2 (mutant) + ubiquitin + otub1 + ubiquitin aldehyde
    
  • 4wz3, 6w7z – hUbc D2 + E3 ubiquitin-protein ligase LubX
    
  • 7ahz, 7ai0, 7ai1, 7r71 – hUbc D2 + E3 ubiquitin-protein ligase RNF165+ Ub
    
  • 6w7z, 6w9d – hUbc D2 + E3 ubiquitin-protein ligase RLIM + Ub
    
  • 8b3i – hUbc D2 + E3 ubiquitin-protein ligase RBX1 + polyubiqiutin-C + NEDD8 – Cryo EM
    
  • 5v2w – hUbc D2 (mutant) + ubiquitin + TRIM23
    
  • 1ur6 – hUbc D2 + Cnot4 - NMR
    
  • 4auq, 6hpr – hUbc D2 (mutant) + baculoviral IAP repeat-containing protein + ubiquitin
    
  • 3jvz, 3jw0 – hUbc D2 (mutant) + E3 NEDD4-2 + ubiquitin
    
  • 6ttu – hUbc D2 in Cullin RING E3 ligase- Cryo EM
    
  • 3eb6 – fUbc D2 + baculoviral IAP repeat-containing protein- frog
    
• Ubiquitin conjugating enzyme D3
  • 5egg, 1x23 – hUbc D3
    
  • 5ifr – hUbc D3 + ubiquitin
    
  • 2fuh – hUbc D3 + ubiquitin - NMR
    
  • 3ugb – hUbc D3 (mutant) + ubiquitin
    
  • 3l1z – hUbc D3 + ubiquitin conjugating factor
    
  • 4s3o, 3rpg – hUbc D3 + polycomb group ring finger protein + E3 ubiquitin-protein ligase RING2
    
  • 4bvu – hUbc D3 + OspG + ubiquitin
    
  • 6cp0 – hUbc D3 + SdcA
    
  • 6t7f – hUbc D3 + ubiquitin + E3 ubiquitin-protein ligase MYCBP2
    
  • 7lyb, 8grq, 8smw, 8smy, 8u14, 8upf – hUbc D3 in nucleosome complex – Cryo EM
    
  • 7jzv, 8smw, 8smx, 8smz, 8sn0, 8sn1, 8sn2, 8sn3, 8sn4, 8sn5, 8sn7, 8sn8 – hUbc D3 (mutant) in nucleosome complex – Cryo EM
    
• Ubiquitin conjugating enzyme E1
  • 3bzh, 5lbn – hUbc E1
    
  • 8iya – hUbc E1 (mutant) + SETDB1 peptide
    
  • 6fga – hUbc E1 + E3 TRIM21
    
• Ubiquitin conjugating enzyme E2
  • 6w9a – hUbc E2 + E3 ubiquitin-protein ligase RLIM
    
• Ubiquitin conjugating enzyme G1
  • 6d68 – hUbc G1 + ubiquitin
    
• Ubiquitin conjugating enzyme G2
  • 2cyx – hUbc
    
  • 2kly – hUbc - NMR
    
  • 3fsh – hUbc + autocrine motility factor receptor
    
  • 2lxp – hUbc + AMFR peptide - NMR
    
  • 3h8k, 4lad – hUbc + AMFR peptide
    
  • 7lew – hUbc + AUP1 peptide
    
• Ubiquitin conjugating enzyme H
  • 2z5d – hUbc
    
• Ubiquitin conjugating enzyme J2
  • 2f4w – hUbc
    
• Ubiquitin conjugating enzyme K
  • 5dfl, 6if1, 7myf – hUbc + ubiquitin
    
  • 6jb6, 6jb7 – hUbc (mutant) + ubiquitin
    
  • 7ojx – hUbc + polyubiquitin-B + E3 ubiquitin-protein ligase RNF38
    
• Ubiquitin conjugating enzyme L6
  • 8se9, 8sea, 8sv8 – hUbc + Uba7 + ISG15 – Cryo EM
    
• Ubiquitin conjugating enzyme Q1
  • 2qgx – hUbc
    
• Ubiquitin conjugating enzyme R1
  • 3rz3, 7m2k – hUbc + inhibitor
    
  • 4mdk – hUbc + ubiquitin + inhibitor
    
• Ubiquitin conjugating enzyme R2
  • 6nyo – hUbc R2 + ubiquitin
    
  • 8pql, 8q7r – hUbcR2 in cullin-ring ligase complex – Cryo EM
    
• Ubiquitin conjugating enzyme S
  • 1zdn – hUbc
    
  • 7ahf – hUbc (mutant)
    
  • 6qhk, 6s98 – hUbc catalytic domain
    
  • 6qh3, 6s96 – hUbc catalytic domain (mutant)
    
  • 5bnb – hUbc + ubiquitin
    
• Ubiquitin conjugating enzyme T
  • 6r75 – hUbc T (mutant)
    
  • 4ccg – hUbc T + E3 ubiquitin-protein ligase Fancl
    
  • 8jve – hUbc + inhibitor
    
• Ubiquitin conjugating enzyme Uev-1
  • 2a4d – hUbc catalytic domain
    
  • 2hlw – hUbc catalytic domain - NMR
    
  • 3e95 – PfUbc + ubiquitin carrier protein
    
• Ubiquitin conjugating enzyme Z
  • 5a4p – hUbc Z
    
• Ubiquitin conjugating enzyme E2-18KDa
  • 6op8 – fyUbc + CUE domain-containing protein 4
    
• Ubiquitin conjugating enzyme E2-21KDa
  • 2y9m – yUbc Ubc domain 15-183 + peroxisome assembly protein
    
• Ubiquitin conjugating enzyme E2-25KDa (Huntington interacting protein 2 HIP-2)
  • 1yla, 2bep – hHIP-2
    
  • 3e46 – hHIP-2 (mutant)
    
  • 2bf8 – hHIP-2 + SUMO
    
  • 2o25 – hHIP-2 + Ubc9
    
  • 3f92 – hHIP-2/azorectase (mutant)
    
  • 3k9o, 3k9p – hHIP-2 + ubiquitin
    
  • Ubiquitin conjugating enzyme E2-34KDa
  • 6zhu, 7k5j – yUbc + E1 + ATP
    
• Ubiquitin conjugating enzyme E2-230KDa
  • 7un6 – yUbc + NAP1L1 – Cryo EM