Crystal structure of the topoisomerase VI holoenzyme from Methanosarcina mazeiCrystal structure of the topoisomerase VI holoenzyme from Methanosarcina mazei

Structural highlights

2q2e is a 2 chain structure with sequence from Methanosarcina mazei. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 4Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TOP6A_METMA Relaxes both positive and negative superturns and exhibits a strong decatenase activity (By similarity).[HAMAP-Rule:MF_00132]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2q2e, resolution 4.00Å

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