Solution structure of the endonuclease Nob1 from P.horikoshiiSolution structure of the endonuclease Nob1 from P.horikoshii

Structural highlights

2lcq is a 1 chain structure with sequence from Pyrococcus horikoshii OT3. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NOB1_PYRHO Toxic component of a toxin-antitoxin (TA) module (Potential). Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end.[1]

References

  1. Veith T, Martin R, Wurm JP, Weis BL, Duchardt-Ferner E, Safferthal C, Hennig R, Mirus O, Bohnsack MT, Wohnert J, Schleiff E. Structural and functional analysis of the archaeal endonuclease Nob1. Nucleic Acids Res. 2012 Apr 1;40(7):3259-74. Epub 2011 Dec 10. PMID:22156373 doi:10.1093/nar/gkr1186
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