2kx4

Solution structure of Bacteriophage Lambda gpFIISolution structure of Bacteriophage Lambda gpFII

Structural highlights

2kx4 is a 1 chain structure with sequence from Escherichia virus Lambda. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FII_LAMBD Plays a role in virion assembly by joining the head and the tail at the last step of morphogenesis. Six FII proteins bind the DNA-filled capsid after W binding, in turn binding the pre-assembled tail by interacting with U protein.^[1] ^[2] ^[3]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Boklage CE, Wong EC, Bode VC. Functional abnormality of lambda phage particles from complemented FII-mutant lysates. Virology. 1974 Sep;61(1):22-8. PMID:4413519
↑ Casjens S. Bacteriophage lambda FII gene protein: role in head assembly. J Mol Biol. 1974 Nov 25;90(1):1-20. PMID:4616093
↑ Casjens S, Horn T, Kaiser AD. Head assembly steps controlled by genes F and W in bacteriophage lambda. J Mol Biol. 1972 Mar 14;64(3):551-63. PMID:5022189

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OCA

[1] Boklage CE, Wong EC, Bode VC. Functional abnormality of lambda phage particles from complemented FII-mutant lysates. Virology. 1974 Sep;61(1):22-8. PMID:4413519

[2] Casjens S. Bacteriophage lambda FII gene protein: role in head assembly. J Mol Biol. 1974 Nov 25;90(1):1-20. PMID:4616093

[3] Casjens S, Horn T, Kaiser AD. Head assembly steps controlled by genes F and W in bacteriophage lambda. J Mol Biol. 1972 Mar 14;64(3):551-63. PMID:5022189

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