2jvh

Structure of C3-binding domain 4 of S. aureus protein SbiStructure of C3-binding domain 4 of S. aureus protein Sbi

Structural highlights 2jvh is a 1 chain structure with sequence from Staphylococcus aureus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Solution NMR Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function SBI_STAAM Plays a role in the inhibition of both the innate and adaptive immune responses. Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b and CFH. By recruiting CFH and C3b, the secreted form acts as a potent complement inhibitor of the alternative pathway-mediated lysis.[UniProtKB:A6QJQ7]

spinqualitylabelsall models 2jvh Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image