2jqe

Soution Structure of Af54 M-domainSoution Structure of Af54 M-domain

Structural highlights

2jqe is a 1 chain structure with sequence from Archaeoglobus fulgidus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SRP54_ARCFU Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (Probable).^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Bhuiyan SH, Gowda K, Hotokezaka H, Zwieb C. Assembly of archaeal signal recognition particle from recombinant components. Nucleic Acids Res. 2000 Mar 15;28(6):1365-73. PMID:10684931

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OCA

[1] Bhuiyan SH, Gowda K, Hotokezaka H, Zwieb C. Assembly of archaeal signal recognition particle from recombinant components. Nucleic Acids Res. 2000 Mar 15;28(6):1365-73. PMID:10684931

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