Crystal Structure of Sep-tRNA:Cys-tRNA Synthase from Archaeoglobus fulgidusCrystal Structure of Sep-tRNA:Cys-tRNA Synthase from Archaeoglobus fulgidus

Structural highlights

2e7j is a 2 chain structure with sequence from Archaeoglobus fulgidus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

SPSS1_ARCFU Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).[1]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Fukunaga R, Yokoyama S. Structural insights into the second step of RNA-dependent cysteine biosynthesis in archaea: crystal structure of Sep-tRNA:Cys-tRNA synthase from Archaeoglobus fulgidus. J Mol Biol. 2007 Jun 29;370(1):128-41. Epub 2007 May 4. PMID:17512006 doi:10.1016/j.jmb.2007.04.050

2e7j, resolution 2.40Å

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