Solution structure of the SMR domain of NEDD4-binding protein 2Solution structure of the SMR domain of NEDD4-binding protein 2

Structural highlights

2d9i is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

N4BP2_HUMAN Has 5'-polynucleotide kinase and nicking endonuclease activity. May play a role in DNA repair or recombination.[1]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Watanabe N, Wachi S, Fujita T. Identification and characterization of BCL-3-binding protein: implications for transcription and DNA repair or recombination. J Biol Chem. 2003 Jul 11;278(28):26102-10. Epub 2003 May 2. PMID:12730195 doi:10.1074/jbc.M303518200
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