Cyclophilin from Trypanosoma cruzi bound to cyclosporin ACyclophilin from Trypanosoma cruzi bound to cyclosporin A

Structural highlights

1xq7 is a 6 chain structure with sequence from Tolypocladium inflatum and Trypanosoma cruzi. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.07Å
Ligands:, , , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q4DPB9_TRYCC PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.[RuleBase:RU004223]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1xq7, resolution 2.07Å

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OCA