Extragenic suppressor from Pyrococcus furiosus Pfu-1862794-001Extragenic suppressor from Pyrococcus furiosus Pfu-1862794-001

Structural highlights

1xi6 is a 1 chain structure with sequence from Pyrococcus furiosus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.8Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FBP_PYRFU Catalyzes the conversion of D-fructose 1,6-bisphosphate to D-fructose 6-phosphate. In vitro, has also weak activity with inositol-1-phosphate, glucose-1-phosphate and glycerol-2-phosphate.[1]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Verhees CH, Akerboom J, Schiltz E, de Vos WM, van der Oost J. Molecular and biochemical characterization of a distinct type of fructose-1,6-bisphosphatase from Pyrococcus furiosus. J Bacteriol. 2002 Jun;184(12):3401-5. PMID:12029059 doi:10.1128/JB.184.12.3401-3405.2002

1xi6, resolution 2.80Å

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