Crystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in inhibitor-bound formCrystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in inhibitor-bound form
Structural highlights
1wyv is a 8 chain structure with sequence from Thermus thermophilus HB8. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Q5SKW8_THET8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity).[HAMAP-Rule:MF_00712][SAAS:SAAS023010_004_045580]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
