Proteopedia

1wwy

Solution structure of the DUF1000 domain of a thioredoxin-like protein 1Solution structure of the DUF1000 domain of a thioredoxin-like protein 1

Structural highlights

1wwy is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

TXNL1_HUMAN Active thioredoxin with a redox potential of about -250 mV.[1]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Andersen KM, Madsen L, Prag S, Johnsen AH, Semple CA, Hendil KB, Hartmann-Petersen R. Thioredoxin Txnl1/TRP32 is a redox-active cofactor of the 26 S proteasome. J Biol Chem. 2009 May 29;284(22):15246-54. doi: 10.1074/jbc.M900016200. Epub 2009, Apr 6. PMID:19349277 doi:http://dx.doi.org/10.1074/jbc.M900016200
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