Solution structure of the Villin headpiece domain of human actin-binding LIM protein homologue (KIAA0843 protein)Solution structure of the Villin headpiece domain of human actin-binding LIM protein homologue (KIAA0843 protein)

Structural highlights

1ujs is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

ABLM3_HUMAN May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity.[1]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Barrientos T, Frank D, Kuwahara K, Bezprozvannaya S, Pipes GC, Bassel-Duby R, Richardson JA, Katus HA, Olson EN, Frey N. Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin. J Biol Chem. 2007 Mar 16;282(11):8393-403. Epub 2006 Dec 28. PMID:17194709 doi:http://dx.doi.org/M607549200
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