1m42

Solution structure of apoCopC from Pseudomonas syringaeSolution structure of apoCopC from Pseudomonas syringae

Structural highlights 1m42 is a 1 chain structure with sequence from Pseudomonas syringae. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Solution NMR Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function Q4ZWC7_PSEU2 Involved in copper resistance.[RuleBase:RU369037] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed The structure of the metal-free form of CopC, a protein involved in copper homeostasis, has been obtained. The fold is a Greek key beta barrel similar to that of functionally unrelated blue copper proteins but with important structural variations. The protein binds one equivalent of copper (II) with relatively high affinity and contains a cluster of conserved residues (His1, Glu27, Asp89, and His91) which could form a water-accessible metal binding site. The structure also reveals a loop containing the M(X)(n)M motif which is present in a number of proteins also involved in copper homeostasis. The present structure represents a link between copper-trafficking proteins and cupredoxins. Within a structural and genomic analysis, the role of CopC in copper trafficking is discussed. Solution structure of CopC: a cupredoxin-like protein involved in copper homeostasis.,Arnesano F, Banci L, Bertini I, Thompsett AR Structure. 2002 Oct;10(10):1337-47. PMID:12377120 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

spinqualitylabelsall models 1m42 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image