Theoretical Model: The protein structure described on this page was determined theoretically, and hence should be interpreted with caution.

THEORETICAL MODEL OF P-SELECTIN, C-TYPE LECTIN DOMAIN, RESIDUES 1-120, CELL ADHESION MOLECULETHEORETICAL MODEL OF P-SELECTIN, C-TYPE LECTIN DOMAIN, RESIDUES 1-120, CELL ADHESION MOLECULE

Structural highlights

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Resources:FirstGlance, PDBsum, ProSAT

Publication Abstract from PubMed

We describe how to build protein models from structural templates. Methods to identify structural similarities between proteins in cases of significant, moderate to low, or virtually absent sequence similarity are discussed. The detection and evaluation of structural relationships is emphasized as a central aspect of protein modeling, distinct from the more technical aspects of model building. Computational techniques to generate and complement comparative protein models are also reviewed. Two examples, P-selectin and gp39, are presented to illustrate the derivation of protein model structures and their use in experimental studies.

Knowledge-based model building of proteins: concepts and examples.,Bajorath J, Stenkamp R, Aruffo A Protein Sci. 1993 Nov;2(11):1798-810. PMID:7505680[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

  1. Bajorath J, Stenkamp R, Aruffo A. Knowledge-based model building of proteins: concepts and examples. Protein Sci. 1993 Nov;2(11):1798-810. PMID:7505680
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