Crystal Structure of Cyclic Bovine Pancreatic Trypsin InhibitorCrystal Structure of Cyclic Bovine Pancreatic Trypsin Inhibitor

Structural highlights

1k6u is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

BPT1_BOVIN Inhibits trypsin, kallikrein, chymotrypsin, and plasmin.

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The crystal structure of a cyclic form of a mutant of bovine pancreatic trypsin inhibitor has been solved at 1.0 A resolution. The protein was synthesized by native chemical ligation and its structure is almost indistinguishable from the previously described recombinant form of the same mutant; however, the new loop containing the former termini became much better ordered.

Crystal structure of a cyclic form of bovine pancreatic trypsin inhibitor.,Botos I, Wu Z, Lu W, Wlodawer A FEBS Lett. 2001 Nov 30;509(1):90-4. PMID:11734212[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

See Also

References

  1. Botos I, Wu Z, Lu W, Wlodawer A. Crystal structure of a cyclic form of bovine pancreatic trypsin inhibitor. FEBS Lett. 2001 Nov 30;509(1):90-4. PMID:11734212

1k6u, resolution 1.00Å

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