1cja

ACTIN-FRAGMIN KINASE, CATALYTIC DOMAIN FROM PHYSARUM POLYCEPHALUMACTIN-FRAGMIN KINASE, CATALYTIC DOMAIN FROM PHYSARUM POLYCEPHALUM

Structural highlights

1cja is a 2 chain structure with sequence from Physarum polycephalum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.9Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AFK_PHYPO Has a role in the regulation of microfilament formation. Phosphorylates the actin-fragmin complex on threonine residues, in vitro.^[1] ^[2] ^[3]

References

↑ Eichinger L, Bomblies L, Vandekerckhove J, Schleicher M, Gettemans J. A novel type of protein kinase phosphorylates actin in the actin-fragmin complex. EMBO J. 1996 Oct 15;15(20):5547-56. PMID:8896448
↑ Furuhashi K, Hatano S. Actin kinase: a protein kinase that phosphorylates actin of fragmin-actin complex. J Biochem. 1992 Mar;111(3):366-70. PMID:1587799
↑ Furuhashi K, Hatano S, Ando S, Nishizawa K, Inagaki M. Phosphorylation by actin kinase of the pointed end domain on the actin molecule. J Biol Chem. 1992 May 5;267(13):9326-30. PMID:1315751

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Eichinger L, Bomblies L, Vandekerckhove J, Schleicher M, Gettemans J. A novel type of protein kinase phosphorylates actin in the actin-fragmin complex. EMBO J. 1996 Oct 15;15(20):5547-56. PMID:8896448

[2] Furuhashi K, Hatano S. Actin kinase: a protein kinase that phosphorylates actin of fragmin-actin complex. J Biochem. 1992 Mar;111(3):366-70. PMID:1587799

[3] Furuhashi K, Hatano S, Ando S, Nishizawa K, Inagaki M. Phosphorylation by actin kinase of the pointed end domain on the actin molecule. J Biol Chem. 1992 May 5;267(13):9326-30. PMID:1315751

[1]

[2]

[3]